On September 16
335 BC Alexander the Great destroyed every building in Thebes, Egypt, except the temples and the house of the poet Pindar.
1386 St. Ambrose of Camaldoli was born. Ambrose helped bring about a brief reunion of the Eastern and Western churches.
1387 King Henry V of England was born.
1400 Owain Glyndwr proclaimed himself Prince of Wales, launching the last Welsh rebellion against the English.
1494 Francisco Maurolico was born. He was a Benedictine monk, historian, and mathematician, Maurolico wrote a history of Sicily and significant works on Greek mathematics.